Searchable abstracts of presentations at key conferences in endocrinology

ea0011p191 | Clinical practise and governance | ECE2006

Concordance between GH determination and IGF-I in acromegaly using two IGF-I methods

Hepburn S , Chambers SM , Gilbert JA , McGregor AM , Miell JP , Aylwin SJB

Introduction and aims: Following treatment for acromegaly, both growth hormone (GH) and insulin-like growth factor-I (IGF-I) levels are predictive of mortality. These data are derived from studies of either a single GH or the mean circadian GH, with a threshold of 2 mcg/l. However, consensus target criteria (Giustina et al. 2000) require: a nadir GH of <1 mcg/l on OGTT and IGF-I within the age/sex-adjusted normal range. We aimed to determine the degree to which norm...